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We have reviewed the records of 65 symptomatic patients with B hominis in their stool. We conclude that B hominis is a potential pathogen that may or may not require drug therapy depending on the overall clinical circumstances, the severity of symptoms, and the presence of other pathogenic organisms.
Blastocystis hominis--a potential intestinal pathogen.
R R Babb and S Wagener
West J Med. 1989 November; 151(5): 518-519.
The search for (Blastocystis hominis) should be a parasitological routine analysis since it is the cause of frequent intestinal disorders.
Ponce de Leon P, Svetaz MJ, Zdero M. Rev Latinoam Microbiol. 1991 Apr-Sep;33(2-3):159-64
The most usual complaint of Blastocystosis patients is of intense abdominal discomfort accompanied by pain. Diarrhoea is not standard, and constipation is common. The symptoms gleaned from the literature include abdominal pain, discomfort, anorexia, bloating, cramps, diarrhoea, constipation, alternating diarrhoea and constipation, watery diarrhoea, mucus diarrhoea, vomiting, dehyratation, sleeplessness, nausea, weight loss, inability to work, lassititude, dizziness, flatus, pruritis, and tenesmus. Blood in the stool as well as excessive mucus and leucocytes have been reported. Moderate to severe eosinophilia is not uncommon and was reported in 8 of 19 patients in one study.
Blastocystis hominis - Past and Future. Charles H. Zierdt. Clinical Micro. Reviews. Jan 1991, p. 61-79.
The clinician should be aware of B.hominis as a possible cause of diarrhoea and other symptoms, particularly when the parasite burden is high.
Clinical Relevance of Blastocystis hominis.
Lancet June 2, 1984
B. hominis has been reported in patients with intestinal symptoms, intestinal obstruction due to carcinoma, in AIDS patients with diarrhoea, and in patients with Irritable Bowel Syndrome.
Letter to the editor.
British Journal of Biomedical Science 2001; 58:129-130
Windsor, MacFarlane, Whiteside, Chalmers, Thomas & Joynson.
The clinician should be aware of B.hominis as a possible cause of diarrhoea and other symptoms, particularly when the parasite burden is high.
Clinical Relevance of Blastocystis hominis.
Lancet June 2, 1984
We believe this case provides further evidence to support the pathogenicity of B. hominis.
Hemorrhagic Proctosigmoiditis and Blastocystis hominis infection
Annals of Internal Medicine.
Volume 124(2) Jan. 15, 1996. 278-279
Loose stools, diarrhea, stomach pain, and stomach cramping are the most common symptoms. Loss of weight and appetite, nausea, and fatigue also are common symptoms.
referenced from the Center for Disease Control website on D.fragilis
Blastocystis hominis is increasingly recognized to be a cause of human enteric disease, with symptoms often like those in giardiosis.
Lipid Peroxidation Level in Patients with Blastocystosis
Eser Kiliç*, Süleyman Yazar**, Recep Saraymen,
Inönü Üniversitesi Tip Fakültesi Dergisi 10(1) 1-3 (2003)
Blastocystis hominis can cause terminal ileitis in patients, without any apparent predisposing factors.
Crohn's Disease and Infections: A Complex Relationship.
Medscape/WebMD. 2005
Symptoms commonly attributed to infection with B. hominis
are nonspecific and include diarrhea; abdominal pain, cramps,
or discomfort; and nausea. Profuse,
watery diarrhea has been reported in acute cases, although this may be less pronounced in chronic cases. Fatigue, anorexia, flatulence, and other nonspecific gastrointestinal
effects also may be associated with B. hominis
infection. Fever has been reported, particularly
in acute cases, but has not been noted in other studies.
Other signs and symptoms
sometimes reported include fecal leukocytes, rectal bleeding, eosinophilia, hepatomegaly and splenomegaly , cutaneous rashes, and itching. One report has indicated that joint pains
and swelling may result from infection of the synovial fluid by
B. hominis.
Blastocystis hominis Revisited
Stenzel & Boreham.
Clinical Micro. Reviews.
Oct. 1996, Vol. 9, No. 4. p. 563–584
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Blastocystis hominis symptoms
I cannot give any scientist of any age better advice than this: the intensity of a conviction that a hypothesis is true has no bearing on whether it is true. The importance of the strength of our conviction is only to provide a proportionately strong incentive to find out if the hypothesis will stand up to critical examination.
- Peter B. Medawar, zoologist and immunologist, Advice to a Young Scientist, 1979
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"After having symptoms for about 5 years now I finally found a doctor that considered the possibility of intestinal parasites and have since been diagnosed with Blasto. by the Great Smokies Lab.
It feels like I am dying a slow death..."
September 2005, USA
The GI who called me and insisted that this is non-pathogenic - the doctor works at a prominent University hospital and is a Harvard graduate. In fact she actually told me that they no longer test for this at her hospital. In other words, she works in the IBS division of this huge hospital (it can take up to 6 months just to get an appt with them - that's how back logged they are), where they diagnose and "treat" hundreds of IBS, but never test them for BH because she believes that unless you are elderly, an AIDS patient or an infant, BH cannot cause illness.
November 05, USA
(Click here to read similar examples of Medical Mismanagement)
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The most common symptoms reported with B. hominis infection include diarrhoea, nausea, abdominal pain, cramps, discomfort and flatulence. Other less frequently reported symptoms include fever, constipation, vomiting, eosinophilia, anorexia, fatigue and non-specific gastrointestinal effects.
D. fragilis and B. hominis: neglected human protozoa. J. J. Windsor. The Biomedical Scientist. July 2007. Pages 524-27. |
Click here to read symptoms described in medical literature.
Other symptoms reported to this site:
Cravings for sweets/starchy foods (see Diet);
Food sensitivites - particularly to high carb foods, fruit and sweets.
Thick white/grey tongue coating;
Undigested food particles in stool;
Nervous and sensory disorders including inability to concentrate, depression, panic attacks. brain fog, sleep disturbances, depression and feelings of doom.
Fatigue.
Hot and cold sweats.
I have been diagnosed through Great Smokies Diagnostic laboratory in the US
with 'many' blastocystis hominis....my symptoms are extreme fatigue and brain
fog "
L. 19 March 03
"I have been suffering from the following symptoms over a period of approximately 8 months: flatulence, loose stools, dizziness, hot and cold sweats, neckache, elevated heartbeat, lower back pain, bloating, weakness, shakes, loss of appetite, cravings for sweet foods, feelings of death, general feeling of unwellness. January 2003 I diagnosed with Blastocystis Hominis infection after asking to have a stool test.
I requested this test because a friend of my wife's had been suffering with similar symptoms and was found to have Intestinal Parasites."
March 03
"I have (been diagnosed with Blasto) and experienced abdominal pain and fatigue consistently".
A. 28 Feb. 03
"I am from the eastern USA. I have been suffering for the last eight months from general gastritis, excess amount of gas, belching, general weakness, abdominal pain and waking up from a sound sleep during the night with abdomen pain. The abdomen pain goes away with food. Sometimes I get spasms which also goes away taking some anti-spasmatic medicine."
H. Diagnosed with B.hominis, August 02
"I have an itchy bottom;
incredibly poor digestion; excess gas and bloating; decreased physical capacity. it took a long time for me to be diagnosed, and i've been ill for the better part of a year. My doctor described B.Hominis as a "benign parasite" and said it couldn't possibly be causing my symptoms.
I've been treated with flagyl, for 7 days but not
much difference"
(Queensland man with Blasto., October 2005)
Medically documented symptoms:
Click here to read a complete of 19 symptomatic patients
infected with Blastocystis hominis.
Association of Blastocystis hominis with signs and symptoms of human disease. D J Sheehan, et al. J Clin Microbiol. 1986 October; 24 (4): 548-550
Purged stools from 389 patients were evaluated microscopically for the presence of Blastocystis hominis. A total of five or more B. hominis cells per 40X field were observed in 43 patients (11%), and B. hominis was the only intestinal parasite present in 23 (6%) of these patients. Of the 23 patients, 19 had symptoms which included abdominal discomfort (15 patients), anorexia (10 patients), diarrhea (9 patients), and flatus (9 patients) . The remaining four patients were asymptomatic.
Two apparently healthy children from the same family were found to have moderate to heavy Blastocystis hominis in their stool samples whilst being investigated for intestinal symptoms:
sporadic, painless, rectal bleeding in one and persistent diarrhea in the other.
Blastocystis hominis in two children of one family
West Indian Med J 1990 Mar;39(1):57-8 . Bratt DE, Tikasingh ES.
We describe a unique case of severe Blastocystis hominis infection in an elderly man with severe dehydration, marked leukocytosis and hypoalbuminaemia after antibiotic treatment for right pneumonia. The patient recovered after treatment with metronidazole. This case presentation demonstrates the ability of B. hominis to induce severe gastrointestinal manifestations and general deterioration, particularly in light of the controversy surrounding its possible potential pathogenicity.
Severe Blastocystis hominis in an elderly man. J Infect 1996 Jul;33(1):57-9 Arch Intern Med 1988 May;148(5):1064
We describe the case of a ten year-old girl who was admitted to our hospital for diarrhea, abdominal pain and fever . The presence of B. hominis was demonstrated in her stools. The patient responded favourably to treatment with metronidazole. We feel that our observation is an additional support to recognition of B. hominis as a human pathogen.
Blastocystis hominis infection: a case report. Antonelli F et al. Minerva Pediatr 1996 Dec;48(12):571-3
The most usual complaint of blastocystis patients is of intense abdo. discomfort accompanied by pain. Diarrhea is not standard, and constipation is common. The symptoms gleaned from the literature include abdo. pain, discomfort, anorexia, bloating, cramps, diarrhea, constipate, alternating diarrhea and constipation, watery diarrhea, mucus diarrhea, vomiting, dehydration, sleeplessness, nausea, weight loss, inability to work, lassitude, dizziness, flatus, pruritus, and tenesmus.
Blood in the stool as well as excessive mucus and leukocytes have been reported. Moderate to severe eosinophilia is not uncommon and was reported in 8 of 19 patients in one study.
Blastocystis hominis - Past and Future. Clin. Micro. Reviews. Jan 1991 p. 61-79
Twenty-nine patients were asymptomatic (59%), and 20 had symptoms of bloating, flatulence, soft/loose stools, or constipation.
Blastocystis hominis in hospital employees. Am J Gastroenterol 1992 Jun;87(6):729-32
Of the 23 patients, 19 had symptoms which included abdominal discomfort (15 patients), anorexia (10 patients), diarrhea (9 patients), and flatus (9 patients).
Association of Blastocystis hominis with signs and symptoms of human disease.
J Clin Microbiol 1986 Oct;24(4):548-50
The most frequent symptomatology in patients with B. hominis only was: abdominal pains, pruritus, flatulence, malaise, anorexia and diarrhea. Only 14.9% did not present any symptoms at all.
Isolate resistance of Blastocystis hominis to metronidazole (Flagyl).
Trop Med Int Health 1999 Apr;4(4):274-7
The clinical picture of B. hominis consists of non specific abdominal pain, watery diarrhea, anorexia, vomiting and weight loss. Rarely, a more invasive form of the disease with rectal bleeding can occur.
Blastocystis hominis infection: a case report. Minerva Pediatr 1996 Dec;48(12):571-3
A study at the Children's Hospital of Pittsburgh in the USA in 1993 found that 85% of children infected with Blasto. experienced gastrointestinal symptoms, including abdominal pain, diarrhoea, vomiting, and weight loss.
Seventy-five percent of these children had been exposed to well water or had travelled to third-world countries.
Prevalence and characteristics of Blastocystis hominis infection in children. Clin Pediatr (Phila) 1993 Feb;32(2):91-6
A 9 month survey carried out on 39 children in a hospital in Kuwait found abdo. pain or discomfort with or without diarhoea was present in 32 children. Only three of the children were diagnosed with other parasites.
Fourteen cases diagnosed as acute experienced cramp-like diarrhoea, watery diarrrhoea and vomiting.
J Trop Med Hyg 1991 Apr;94(2):118-22. Blastocystis hominis infection in children.
A study of 49 hospital employees in New York infected with Blastocystis hominis - 59% were asymptomatic. The remainig 41% experienced bloating, flatulence, soft/loose stools, or constipation.
Am J. Gastroenterology 1992 June;87(6):729-32. Blastocystis hominis in hospital employees.
Fifty-two patients at a teaching hospital in the US found without concomitant parasitic infection or bacterial pathogens in stool experienced gastrointestinal symptoms. The highest reported symptom was abdominal pain, diarrhea and five patients experienced vomiting. In 50 of these patients Blasto only was identified in stool samples.
J Clin Gastroenterol 1990 Oct;12(5):525-32. Frequency of recovery of Blastocystis hominis in clinical practice.
Of 143 at a Canadian hospital where B.hominis was the only parasite found:
19 patients were asymptomatic
15 had symptoms of acute gastroenteritis
21 had chronic gastroenteritis
One hundred and thirty of these patients reported watery diarrhoea, abdo. pain and gas.
J Clin Microbiol 1990 Jan;28(1):116-21. Epidemiology and pathogenicity of Blastocystis hominis.
Symptoms of B. hominis in a hospital in Saudi Arabia found the most common symptoms were abdominal pain (87.9%), constipation (32.2%), diarrhea (23.4%), alternating diarrhea and constipation (14.5%), vomiting (12.5%), and fatigue (10.5%).
Clinical significance of Blastocystis hominis. Qadri SM, al-Okaili GA, al-Dayel F. Department of Pathology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
see also Other illnesses
and Medical Mismanagement
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